FAST DISSOLVING TABLETS OF PIMOZIDE: DESIGN, OPTIMIZATION AND INVITRO CHARACTERIZATION
نویسندگان
چکیده
منابع مشابه
Formulation Design and Optimization of Fast Dissolving Clonazepam Tablets
Fast dissolving tablets of clonazepam were prepared by direct compression method with a view to enhance patient compliance. A 3(2) full factorial design was applied to investigate the combined effect of two formulation variables: amount of crospovidone and microcrystalline cellulose. Crospovidone (2-8% w/w) was used as superdisintegrant and microcrystalline cellulose (20-40% w/w) was used as di...
متن کاملDesign and Evaluation of Fast Dissolving Tablets of Clonazepam
In the present work, fast dissolving tablets of clonazepam were prepared by direct compression method with a view to enhance patient compliance. Three super-disintegrants, viz., crospovidone, croscarmellose sodium and sodium starch glycolate in different ratios with microcrystalline cellulose (Avicel PH-102) along with directly compressible mannitol (Pearlitol SD 200) to enhance mouth feel. The...
متن کاملFast Dissolving Tablets: Preparation, Characterization and Evaluation: an Overview
Oral route is the most preferred route for administration of various drugs because it is regarded as safest, most convenient and economical route. Recently researcher developed the fast dissolving tablet (FDT) with improved patient compliance and convenience. FDTs are solid dosage forms which dissolve rapidly in saliva without chewing and additional water. FDTs overcome the disadvantages of con...
متن کاملFast Dissolving Tablets – Future Aspects
Drug delivery system is an efficient tool for enhancing market, extending product life cycles and creating opportunities. Drug delivery system (DDS) makes a significant contribution to global pharmaceutical sales through market segmentation, and is moving rapidly[1]. Despite of tremendous innovations in drug delivery, the oral route remains the preferred route for administration of therapeutic ...
متن کاملFormulation Design and Optimization of Fast Dissolving Effervescent Tablets of Clonazepam
tablet formulation (t 16.4 min). Short-term stability studies on the formulation indicated that there are no significant changes in drug 50% content and in vitro dispersion time (p<0.05).
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ژورنال
عنوان ژورنال: INDONESIAN JOURNAL OF PHARMACY
سال: 2015
ISSN: 2338-9486,2338-9427
DOI: 10.14499/indonesianjpharm26iss2pp114